Not only do edibles take longer to kick in, but they also last much longer than if you just smoked. Eating a normal dose of an edible product (approximately 10 milligrams) is expected to last 6 hours or longer. Maximum effects should last from the time it starts, until about 3 o'clock, then users generally “settle into their high at that point and slowly rise to a state of relaxation or even sedation. However, you can also expect to be in place for up to 8-12 hours, depending on the strength of the edible and your general tolerance to the herb.
The late onset of the drug effect with ingestion results in a prolonged and persistent high. Cannabis scientist, educator and speaker Alex Samuelsson explains that the source of the prolonged high is the chemical changes that THC undergoes in the body. Samuelsson and Dr. Verbora say that one's individual state at the time of consumption greatly influences how long the high will last.
If you've had too much coffee, it will affect you differently. If you're stressed, it'll affect you differently, Samuelsson says. Since mixing cannabis with drugs or alcohol can often have unpredictable effects, such as paranoia, anxiety, and health problems, Dr. Verbora and Samuelsson don't recommend it.
Remember that not all products are the same and that the high of Sativa, Hybrid or Indica strains can be very different.